Browsing by Author "Karadas, B"
Now showing items 1-12 of 12
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Comparative relaxant effects of YC-1 and DETA/NO on spontaneous contractions and the levels of cGMP of isolated pregnant rat myometrium
Demirkoprulu, N; Cetin, M; Bagcivan, I; Kaya, T; Soydan, AS; Karadas, B; Cetin, A (ELSEVIER SCIENCE BV, 2005)This study was designed to compare the effects of YCA (3-(5-hydroxymethyl-2'-furyl)-1-benzyl indazole), a nitric oxide (NO)independent soluble guanylate cyclase activator, and diethylenetriamine-NONOate (DETA/NO), a NO ... -
Comparison of effects of cyclooxygenase inhibitors on myometrial contraction and constriction of ductus arteriosus in rats
Karadas, B; Kaya, T; Bagcivan, I; Kaloglu, C; Guvenal, T; Cetin, A; Soydan, AS (ELSEVIER SCIENCE BV, 2004)The aim of this study was to compare the tocolytic effect of a selective cylooxygenase-2 inhibitor, DFU (5,5-dimethyl-3(3-fluorophenyl)4-(4-methylsulphonyl)phenyl-2(5H)-furanone), indomethacin and nimesulide on myometrial ... -
Comparison of effects of formoterol and BRL 37344 on isolated term-pregnant rat myometrial strips in vitro
Yurtcu, N; Cetin, A; Karadas, B; Imir, AG; Kaya, T; Erselcan, T; Bagcivan, I; Cetin, M (ELSEVIER SCIENCE BV, 2006)This study was designed to compare the effects of beta-adrenoccptoy agonists formoterol and BRL 37344 on spontaneous contractions and the levels of cAMP and cGMP of myometrial strips isolated from timed-pregnant rats. ... -
Comparison of the effects of nimesulide and 5,5-dimethyl-3-(3-fluorophenyl)-4-(4-methylsulphonyl) phenyl-2(5H)-furanone (DFU) on contractions of isolated pregnant human myometrium
Karadas, B; Kaya, T; Guvenal, T; Cetin, M; Divrik, I; Cetin, A (ELSEVIER SCIENCE BV, 2004)Objective: To compare the effects of 5,5-dimethyl-3-(3-fluorophenyl)-4-(4-methylsulphonyl) phenyl-2(5H)-furanone (DFU) and nimesulide, selective COX-2 inhibitors, on the amplitude and frequency of KCI-, oxytocin-, and ... -
Effect of peritonitis on gallbladder smooth muscle contractility in guinea pigs
Kaya, TT; Koyluoglu, G; Karadas, B; Yildiz, T; Bagcivan, I; Ceran, C; Gokgoz, S (ACADEMIC PRESS INC ELSEVIER SCIENCE, 2004)Background. The mechanisms involved in the impaired gallbladder contractile response in peritonitis are unknown. The aim of this study was to determine the effect of peritonitis on the contraction and relaxation responses ... -
Effects of 5-nitro-2-(3-phenylpropylamino) benzoic acid, anthracene-9-carboxylate, and zaprinast on endothelin-1-induced contractions of pregnant rat myometrium
Kaya, T; Guvenal, T; Karadas, B; Cetin, A; Soydan, AS (ELSEVIER SCI IRELAND LTD, 2002)Objective: The effects of 5-nitro-2-(3-phenylpropylamino) benzoic acid (NPPB), anthracene-9-carboxylate (9-AC) (chloride channel blockers) and zaprinast (an inhibitor of phosphodiesterase-5) on endothelin-1 (ET-1) induced ... -
Effects of ceftriaxone sodium on in vitro gallbladder contractility in guinea pigs
Arpacik, M; Ceran, C; Kaya, T; Karadas, B; Sarac, B; Koyluoglu, G (ACADEMIC PRESS INC ELSEVIER SCIENCE, 2004)Background/Purpose. It has been reported that ceftriaxone may induce the formation of gallstones. Changes of gallbladder motility may play a role in this phenomenon. The present study was designed to analyze the gallbladder ... -
Effects of nimesulide and pentoxifylline on decreased contractile responses in rat ileum with peritonitis
Kaya, TT; Koyluoglu, G; Soydan, AS; Arpacik, M; Karadas, B (ELSEVIER SCIENCE BV, 2002)The aim of this study was to determine the effects of nimesulide and pentoxifylline on the contractile effects of KCl, carbachol and substance P in the longitudinal muscle of rat ileum during peritonitis. Peritonitis was ... -
High-concentration tramadol-induced vasodilation in rabbit aorta is mediated by both endothelium-dependent and -independent mechanisms
Kaya, TJ; Gursoy, SN; Karadas, B; Sarac, B; Kafali, H; Soydan, AS (SHANGHAI INST MATERIA MEDICA, 2003)Aim: The mechanism of tramadol-induced vasodilation was investigated using isolated rabbit thoracic aortic rings. Methods: Aortic rings from 8 rabbits were placed in organ bath and precontracted with phenylephrine (10(-5) ... -
Interactive effect of sevoflurane with isradipine or inclomethacin on spontaneous contractile activity of isolated pregnant rat myometrium
Gursoy, S; Kaya, T; Kunt, N; Karadas, B; Bagcivan, I; Kafali, H (ELSEVIER SCI LTD, 2004)Volatile anesthetics, calcium antagonists and non-steroidal anti-inflammatory drugs inhibit contractile activity of myometrial smooth muscle. The aim of this study was to investigate the interactive effect of sevoflurane ... -
The role of K+ channels on the inhibitor effect of sevoflurane in pregnant rat myometrium
Kafali, H; Kaya, T; Gursoy, S; Bagcivan, I; Karadas, B; Sarioglu, Y (LIPPINCOTT WILLIAMS & WILKINS, 2002)Volatile anesthetics and K+ channel openers inhibit spontaneous contractions in myometrial smooth muscle. Volatile anesthetics modulate K+ channel activity We investigated the role of two K+ channel blockers on the effect ... -
YC-1, a nitric oxide-independent activator of soluble guanylate cyclase, inhibits the spontaneous contractions of isolated pregnant rat myometrium
Cetin, A; Kaya, T; Demirkoprulu, N; Karadas, B; Duran, B; Cetin, M (JAPANESE PHARMACOLOGICAL SOC, 2004)The aim of this study was to investigate the effect of YC-1 (3-(5'-hydroxymethyl-2'-furyl)-1-benzyl indazole) on spontaneous contractions and levels of cyclic GMP (cGMP) of myometrial strips isolated from pregnant rats. ...